store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antipain dihydrochloride (Antipain 2HCl) 是一种从 Actinomycetes 提取到的蛋白酶抑制剂,具有镇痛活性,抑制 X 射线诱导的人淋巴细胞染色体畸变。
产品描述 | Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes. |
体内活性 | Intact, cycling female mice received subcutaneous injections of Antipain dihydrochloride (3 mg) for 16 days, resulting in significant diminution in uterine weight and total DNA compared to untreated controls[1].Antipain dihydrochloride (100 μg/g body weight; i.p.; at 12-hour intervals from 0 to 120 h or 240 to 360 h) exhibits an inhibitory effect on urethane-induced lung neoplasia in mice[2]. |
别名 | Antipain 2HCl, BDBM-32804, BDBM 32804, Antipain, BDBM32804 |
分子量 | 677.62 |
分子式 | C27H46Cl2N10O6 |
CAS No. | 37682-72-7 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Antipain dihydrochloride 37682-72-7 Proteases/Proteasome Protease Antipain 2HCl BDBM-32804 BDBM 32804 Antipain Antipain HCl BDBM 32804, Antipain BDBM32804 Antipain Dihydrochloride Inhibitor inhibitor inhibit